The Advantages of Taking Vitamin D and C. Vitamins D and C play a part in keeping you healthy by promoting strong bones and tissues. However, evidence casts doubt on the idea that they can actually prevent serious diseases in adult life or even minor ailments such as the common cold, according to the University of Maryland Medical Center. Yes, certain supplements may increase or decrease the effectiveness of clopidogrel (Plavix). This can increase the risk of bleeding or, conversely, increase the risk of blood clots. Clopidogrel is a "prodrug," meaning it must be broken down by the body to become active. Two liver enzymes, CYP3A4 and CYP2C19, are responsible for this. Read more about taking vitamin D and magnesium together. Supplementing magnesium and vitamin D. Using vitamin D supplements is particularly important, as you get 80% to 90% of your intake from sunlight rather than diet. While this is fine during the spring and summer when there are more daylight hours, in autumn and winter it can be difficult Applies to: amlodipine and Vitamin C plus Zinc (multivitamin with minerals) Using amLODIPine together with multivitamin with minerals can decrease the effects of amLODIPine. Talk with your doctor before using amLODIPine and multivitamin with minerals together. You may need a dose adjustment or need your blood pressure checked more often if you Nutrition. Ferritin and Vitamin D. As the anemia gets worse, symptoms may include: pale or yellow "sallow" skin. craving for ice or clay, known as pica. sore or smooth tongue. brittle spoon-shaped fingernails and toenails. difficulty swallowing. dark, tar-colored stools or blood in the stool. Taking similar products together can result in an overdose or serious side effects. Avoid the use of salt substitutes in your diet if your multivitamin and mineral contains potassium. The active form of vitamin D, 1,25 (OH)2D, stimulates intestinal calcium absorption, and without sufficient amounts, only 10–15% of dietary calcium and roughly 60% of phosphorus are absorbed 3, 4. With adequate vitamin D, however, calcium and phosphorus absorption are enhanced by 30–40% and 80%, respectively. A deficiency of vitamin D leads Interactions. Folic acid helps to prevent spina bifida in newborns, and it may lower the risk of heart disease and certain cancers. Vitamin D-3 can treat depression and possibly lower the risk of many cancers, as well. Vitamin D-3 and folic acid don't interact negatively with each other, according to the website Drugs.com. People who don’t have an iron deficiency: Taking high amounts of iron supplements when you have normal iron levels can cause side effects. People with hemochromatosis: People with hemochromatosis (iron overload) should avoid iron and vitamin C supplements. Children: The dose of iron in adult supplements is much too high for children. This medicine works better if you take it on an empty stomach. You may take iron and vitamin C with food if it causes an upset stomach. Some foods like eggs, whole grain breads, cereal, dairy products, coffee, and tea may make iron and vitamin C not work as well. If iron and vitamin C causes an upset stomach, talk with your doctor about the it5LF.